Projects

2026
“Projects for joint research teams of the University of Warsaw and WIM-PIB”, funded under Action IV.3.1 “Internal grants of the University of Warsaw to enhance research potential”, Excellence Initiative – Research University.
Application of chemically modified mRNA molecules encoding NICD for targeted activation of the NOTCH pathway to enhance the regenerative potential of progenitor cells (501-D114-20-8004310).
Principal Investigator: Edyta Brzóska-Wójtowicz.

2026
“Projects for joint research teams of the University of Warsaw and WIM-PIB”, funded under Action IV.3.1 “Internal grants of the University of Warsaw to enhance research potential”, Excellence Initiative – Research University.
Impact of NOTCH signaling pathway activation using modified mRNA encoding NICD (Notch Intracellular Domain) on proliferation and survival of cancer and pluripotent cells.
Principal Investigator: Iwona Grabowska-Kowalik.

2024–2028
National Science Centre (NCN), OPUS 26, 2023/51/B/NZ5/00578.
ncRNA as predictors of heterotopic ossification formation.
Principal Investigator: Edyta Brzóska-Wójtowicz.

2023–2027
National Science Centre (NCN), OPUS 24, 2022/47/B/NZ3/00085.
New strategies to support skeletal muscle regeneration – the potential role of microRNA-126.
Principal Investigator: Edyta Brzóska-Wójtowicz.

2022–2026
National Science Centre (NCN), PRELUDIUM, 2021/41/N/NZ5/00504.
Role of CD146+ cells and their progeny in the development and regeneration of mouse skeletal muscles.
Principal Investigator: Bartosz Mierzejewski.

2021–2022
“New Ideas” Programme, Excellence Initiative – Research University.
miRNA as a prognostic factor in heterotopic ossification formation.
Principal Investigator: Edyta Brzóska-Wójtowicz.

2020–2025
National Science Centre (NCN), OPUS 18, 2019/35/B/NZ5/01555.
Functionalized peptide hydrogels as a tool to support skeletal muscle regeneration and enhance the therapeutic properties of myogenic precursor cells.
Principal Investigator: Maria Anna Ciemerych-Litwinienko.

2019–2025
National Science Centre (NCN), OPUS 15, 2018/29/B/NZ5/00613.
Myogenic differentiation of pluripotent stem cells and their potential to support skeletal muscle regeneration – the role of non-coding RNA.
Principal Investigator: Maria Anna Ciemerych-Litwinienko.

2017–2022
National Science Centre (NCN), OPUS 12, 2016/23/B/NZ3/02060.
Potential role of microRNA in stem cell migration during skeletal muscle regeneration.
Principal Investigator: Edyta Brzóska-Wójtowicz.

2016–2020
National Centre for Research and Development (NCBR), STRATEGMED programme, 1/235773/19/NCBR/2016.
Exploitation of the regenerative potential of mesenchymal stem cells.
Principal Investigator: Maria Anna Ciemerych-Litwinienko.

2015–2018
National Centre for Research and Development (NCBR), Applied Research Programme III, PBS3/A7/22/2015.
Development and implementation of a novel method to support skeletal muscle regeneration using adipose-derived mesenchymal stem cells.
Principal Investigator: Maria Anna Ciemerych-Litwinienko.

2014–2017
National Science Centre (NCN), PRELUDIUM, 2013/11/N/NZ3/00186.
Role of Sdf-1 and its receptor Cxcr7 in early stages of embryonic stem cell differentiation.
Principal Investigator: Kamil Kowalski.

2013–2015
National Science Centre (NCN), OPUS 3, 2012/05/B/NZ/0024.
Role of microRNA in myogenic differentiation of embryonic stem cells.
Principal Investigator: Maria Anna Ciemerych-Litwinienko.

2013–2018
National Science Centre (NCN), SONATA 3.
Verification of the role of Wnt in maintaining pluripotency of embryonic stem cells.
Principal Investigator: Karolina Archacka.

2013–2017
National Science Centre (NCN), OPUS 3, 2012/05/B/NZ4/0253.
Role of TGFβ1 in controlling MMP-9 and MMP-2 activity during myoblast differentiation in vitro and skeletal muscle regeneration in vivo.

2012–2015
Foundation for Polish Science (FNP), POMOST Programme, POMOST/2011-4/3.
Participation of stem cells in skeletal muscle regeneration – signaling pathways.
Principal Investigator: Edyta Brzóska-Wójtowicz.

2012–2014
Ministry of Science and Higher Education, Iuventus Plus, 2011 0048/IP/2011/71.
Activation of bone marrow-derived stem cell mobilization to regenerating muscles.
Principal Investigator: Edyta Brzóska-Wójtowicz.

2012–2015
Foundation for Polish Science (FNP), POMOST Programme.
Modification of myogenic potential of pluripotent stem cells – the role of Sonic Hedgehog and interleukin 4.
Principal Investigator: Karolina Archacka.

2010–2013
National Science Centre (NCN), NN302125939.
Embryonic stem cells with pax7-/- genotype as a tool for studying mechanisms of myogenesis.
Principal Investigator: Maria Anna Ciemerych-Litwinienko.

2010–2013
Ministry of Science and Higher Education, NN303548139.
Role of factors controlling myogenesis in differentiation of mouse embryonic stem cells and induced pluripotent stem cells.
Principal Investigator: Iwona Grabowska-Kowalik.

2009–2011
Polpharma Scientific Foundation, 2/VII/2008.
Stimulation of skeletal muscle regeneration – potential role of SDF-1 cytokine.
Principal Investigator: Edyta Brzóska-Wójtowicz.

2009–2012
Ministry of Science and Higher Education, 3040/B/P01/2009/37.
MMP-9 and MMP-2 matrix metalloproteinases in skeletal muscle regeneration in vivo and myoblast differentiation in vitro.

2007–2010
National Science Centre (NCN), NN303308133.
Participation of stem cells in skeletal muscle regeneration – role of myogenic factors and adhesion proteins.
Principal Investigator: Edyta Brzóska-Wójtowicz.

2007–2009
National Science Centre (NCN), N301405133.
Role of adherent human cord blood cells and Wharton’s jelly cells in skeletal muscle regeneration in mice.
Principal Investigator: Maria Anna Ciemerych-Litwinienko.

2006–2009
State Committee for Scientific Research (KBN), 2P04C11230.
Cell adhesion proteins: integrin α3 subunit, tetraspanins CD9 and CD81, ADAM12 – their role in myogenesis and muscle regeneration.
Principal Investigator: Edyta Brzóska-Wójtowicz.